The usual starting dose is 3.75 mg taken just before bedtime when required to help with difficulty sleeping. The recommended adult dose of zopiclone ranges.
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
Withdrawal: Zopiclone can become habit-forming.
Zopiclone products are currently marketed in Canada as 5 mg and 7.5 mg tablets. The 7.5 mg tablet can be split in half to achieve a lower dose.
For additional information, contact the Marketed Health Products Directorate.
Health Canada November 21, 2014.
Health Canada actions:. The current available evidence suggests that next-day impairment may occur in patients the morning following bedtime zopiclone use, including altered driving skills which could lead to accidents.
In one case, excessive daytime drowsiness and fatigue were considered probably related to zopiclone therapy. None of these cases resulted in an accident.
Sixty insomniac patients participated in a controlled double-blind parallel group study designed to investigate the dose-response relationship of zopiclone.
Results of a self-administered sleep questionnaire found a predominantly linear relationship between the dose of zopiclone administered and the degree of sleep improvement. Sixty insomniac patients participated in a controlled double-blind parallel group study designed to investigate the dose-response relationship of zopiclone. Four patients were dropped from the study; two from the placebo group due to ineffectiveness and one each in zopiclone 11.25 mg and 15 mg groups due to side-effects. Although zopiclone was well tolerated at 3.75 mg and 7.5 mg, an increase in side-effects occurred at 11.25 mg and 15 mg, which favours the use of 7.5 mg zopiclone as the optimum dose for most patients, although certain patients may benefit from a higher dose of the drug when well tolerated. Flurazepam 30 mg significantly improved sleep induction and maintenance by comparison to placebo and was indistinguishable from zopiclone 7.5 mg or higher. Clinicians' global impressions showed that the severity of illness clearly decreased in a dose related manner up to zopiclone 11.25 mg. The greatest increment in improvement was generally obtained with 3.5 mg and 7.5 mg of zopiclone, with some additional benefit occurring with zopiclone 11.25 mg. Following 1 day of treatment with placebo, patients were randomly assigned to 1 of 6 groups and received treatment for 7 days with either placebo, or flurazepam 30 mg, or zopiclone, 3.75 mg, 7.5 mg, 11.25 mg or 15 mg.
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7.5mg tablets - no tolerance. Recommended dosage?.
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The most zopiclone SWIM has ever taken is 10mg's, and he is wondering what the highest dose SWIY has ever taken. SWIM is also wondering.
Discussion in ' Downers and sleeping pills ' started by sigurros, Feb 5, 2009.