Moss’s suggestion sounds like a good one. I never alternated like that but I skipped Xyrem nights and did single doses. I would think alternating will reduce both your Xyrem and Ambien tolerance buildup. Xyrem does not effect the benzo site on the GABA receptor so they have only mild cross tolerance at most. Skipping nights altogether and touging it out will help even help more. If you do as Moss says, try and fall asleep naturaly on the Xyrem nights and if you need to sleep due to the next days demands, take your Xyrem after 1-2 hours of trying to sleep. You’ll still get in your two doses. Try single doses and see if you can sleep the remaining part of the night. I could ussualy. Try not to get in the habit of never trying to sleep naturaly or you will never skip doses and never learn you can sleep without drugs. Once you give up compley trying to sleep naturaly, your Physiological dependence will deepen just adding one more layer to your trouble.
This topic contains 13 replies, has 6 voices, and was last updated by mosspa 11 years ago.
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My experience suggests not. Just before I quit using the Z-drugs altogether, I was taking Ambien 2 nights a week, Zopiclone 3 nights a week, and drinking about 4 oz absolute alcohol on Fri and Satr night. You night want to do the spacing differently, though. I’d recommend Xyrem, Xyrem, Xyrem, Ambien, Ambien, Xyrem, Xyrem, Ambien, Ambien, Xyrem, Xyrem, Xyrem, Ambien, Ambien for a 2 week cycle. Also, on Xyrem nights, you should try to see if you can sleep naturally. Do it every Xyrem night since ther is little price to pay given how Xyrem works. Also, remember to not eat for at leat 4 hours on Xyrem nights. I’m sure Z will chime in here somewhere, but it is best to try to get yourself off drug dependent sleep. It’s rough but now I can usualy get a reasonabe night’s sleep after only a couple glasses of wine. Moss.
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Recently I’ve been trying the following: 4 days on Ambien (10 mg) followed by 6 days on Xyrem (6 grms). I had previously used Xyrem successfully for about 8 straight months before it started to lose its effectiveness. I took a 6 month vacation from it and have recently begun using it again. My hope is that it will remain effective longer if I alternate it in this way with the Åmbien. The latter I have never used for more than a few days at a time. My question is this: will such a regimen be likely to cause me to become dependent upon the Ambien? (I’m not worried about becoming dependent upon the Xyrem). Any thoughts or suggestions would be most welcome. Thanks in advance.Ambien bluelight